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Cures confusion. Activates when the Pokemon is confused. One-time use. Provides a one-time 60 Base Power Ground-type attack when a Pokemon holding this item uses Natural Gift.
There are very few reasons to use the Persim Berry. Dragon-types can use the Persim Berry to stop the confusion caused by Outrage (so they can attack again without the risk of attacking themselves). Lum Berry is usually a better option for this though, as it will also prevent other statuses from crippling your Pokemon.