I run a set that goes like this:
Sceptile @Life Orb
Ability: Overgrow
Nature: Timid
Evs: 252HP/ 252SAtk/ 4 Spe
Giga Drain
HP Fire
Dragon Pulse
Substitute
With my three attacking moves I can hit every type (except maybe some dual-types). Giga Drain is to heal my Life Orb recoil and subs...