I play D&D, when I get the chance. I don't really think of it as a board game, though. It's really not hard to find, and 4th Edition has been made a lot more user-friendly. Still helps to have someone experienced to DM it, though, even working off pre-written adventures.
The board games I like include:
- Arkham Horror, although it takes a bit of time to set up.
- Smallworld; an excellent game, highly recommended.
- Pandemic; a fun team-based game, but holy crap is it easy to lose.
- Settlers of Catan.
- Shadows Over Camelot is fun.
- Agricola is okay, but I think it's overrated.
Another few games I really like that are card games rather than board games are Dominion, Citadels, and Ascension.
I loathe Risk. Absolutely loathe it.