As for me, it depends what the bulky mons are.
If defensive, I like using stallbreakers, taunters, and set-up pokemon to screw with them and then the rest of the team. I also like having hazards so if I force the mons out consistently or roar/whirlwind, they take a lot of residual damage.
If offensive, it's best to have super powerful hitters, or depending on the pokemon, something that can threaten really well.
Bulky mons tend to be slow, so I like to abuse their slow speed and strike powerful hits and use status to tear them down.
Edit: But in general, if you can give an idea of the mons, it'll be easier to find a theoretical answer.