I did a few calcs to try to see if changing your EV spread gave you a better chance against some common priority moves. I tested at 0HP/4DEF and 112HP/0DEF, since, as previously stated in the thread, outspeeding 110's (megagross) at +1, seems pretty important so investing any more into HP seems foolish (for a DD set).
Azumaril:
252+ Atk Choice Band Huge Power Azumarill Aqua Jet vs. 0 HP / 4 Def Tyrantrum: 102-121 (33.4 - 39.6%) -- guaranteed 3HKO
252+ Atk Choice Band Huge Power Azumarill Aqua Jet vs. 112 HP / 0 Def Tyrantrum: 103-123 (30.9 - 36.9%) -- 70.7% chance to 3HKO
Bisharp:
252+ Atk Bisharp Sucker Punch vs. 0 HP / 4 Def Tyrantrum: 120-142 (39.3 - 46.5%) -- guaranteed 3HKO
252+ Atk Bisharp Sucker Punch vs. 112 HP / 0 Def Tyrantrum: 120-142 (36 - 42.6%) -- guaranteed 3HKO
Breloom:
252+ Atk Technician Breloom Mach Punch vs. 0 HP / 4 Def Tyrantrum: 186-222 (60.9 - 72.7%) -- guaranteed 2HKO
252+ Atk Technician Breloom Mach Punch vs. 112 HP / 0 Def Tyrantrum: 186-222 (55.8 - 66.6%) -- guaranteed 2HKO
Scizor:
252+ Atk Choice Band Technician Scizor Bullet Punch vs. 0 HP / 4 Def Tyrantrum: 278-330 (91.1 - 108.1%) -- 50% chance to OHKO
252+ Atk Choice Band Technician Scizor Bullet Punch vs. 112 HP / 0 Def Tyrantrum: 278-330 (83.4 - 99%) -- guaranteed 2HKO
Conkeldur:
252+ Atk Conkeldurr Mach Punch vs. 0 HP / 4 Def Tyrantrum: 132-156 (43.2 - 51.1%) -- 2.7% chance to 2HKO
252+ Atk Conkeldurr Mach Punch vs. 112 HP / 0 Def Tyrantrum: 134-158 (40.2 - 47.4%) -- guaranteed 3HKO
Mamoswine:
252 Atk Life Orb Mamoswine Ice Shard vs. 0 HP / 4 Def Tyrantrum: 148-174 (48.5 - 57%) -- 89.1% chance to 2HKO
252 Atk Life Orb Mamoswine Ice Shard vs. 112 HP / 0 Def Tyrantrum: 151-179 (45.3 - 53.7%) -- 32.4% chance to 2HKO
Talonflame(kek):
252+ Atk Choice Band Talonflame Brave Bird vs. 0 HP / 4 Def Tyrantrum: 101-119 (33.1 - 39%) -- 99.9% chance to 3HKO
252+ Atk Choice Band Talonflame Brave Bird vs. 112 HP / 0 Def Tyrantrum: 102-120 (30.6 - 36%) -- 45.1% chance to 3HKO
TL;DR
the damage shift seems pretty minimal overall, and nothing really changed from say a 3HKO to a 2HKO ,except scizor but taking 99% ends you anyway, so trying to minimize priority damage seems kinda unnecessary to me.