Substitute is really useful in the metagame since it makes all the big 2HKO's into 3HKO's. I've been using this set to great success:
Lugia@Leftovers
Trait: Shadow Tag
Timid Nature; everything maxed out
-Spore
-Substitute
-Taunt
-Baton Pass
Lugia was chosen over Blissey because of his incredible base 110 speed. Bring this guy in on something that doesn't have Magic Bounce,Spore, and Pass one of the beefist Substitutes in the game. Shadow Tag insures they won't switch to a Magic Bounce user or someone who can take hits. If you're lucky enough they will still be asleep when you pass. Pass to a hard hitter and something that resists to Extremespeed. My preference is Skill Link Terrakion w/ Shift Gear :O
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