I've used Agility Lucario quite a few times back in the BW1 metagame and the main thing it has over SD is the coverage it's able to run without a general need for priority. SD set always has issues getting around things. Terrakion stops it cold if you don't have Bullet Punch as does Gengar. However, by running this along with ExtremeSpeed, Lucario can do next to nothing against Jellicent, Gliscor, and will not be able to win against any Celebi carrying Earth Power or HP Fire (basically all of them) all of which are threats that Lucario needs Crunch or Ice Punch for respectively. However, Agility fixes your Speed issues and allows you to run full coverage with Close Combat, Crunch, and Ice Punch. (HP Ice with minimal Special Attack investment can be used if beating Gliscor is a must) Coverage usually makes up for the lack in power as long as you have a reliable Spikes user and possibly a wallbreaker. (CB Terrakion for example)
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