[Cherub Agent]

I find the all-out attacker to easily be the best set, simply because Zangoose really relies on Quick Attack to stop itslef from being revenge killed. Although I might test the SD set with a Pursuit user for Ghosts, the problem wih the set in the lower tiers is that Zangoose has basically no opportunity to actually set up a SD. I imagine this will be even harder in UU where everything hits harder

One of the best ways to activate Toxic Orb is just revenge kill a 25% Pokemon with quick attack, and then the orb activates on the following turn.

Although ironically, while Quick attack is excellent for Zangoose, if it runs Shadow Claw it is an excellent Ghostbuster, as it's immune to both burn and their STAB