Nidoqueen's the name, defense is the game.

Nidoqueen

http://www.serebii.net/pokedex-dp/031.shtml

Traits:
Poison Point: When hit with a contact attack, has a 30% chance of poisoning foes.
Rivalry: when facing foes of the same Gender, gets a +1 Attack boost.

Stats:
HP: 90
Atk: 82
Def: 87
SA: 75
SD: 85
Speed: 76

Physical Movepool: (STAB in Bold)
Earthquake
Poison Jab
Poison Fang
Stone Edge
Rock Slide
Avalanche
Focus Punch
Superpower
Brick Break
Crunch
Shadow Claw
Iron Tail
Body Slam
Fire Punch (Tutor)
Ice Punch (Tutor)
Thunderpunch (Tutor)
Aerial Ace
Pursuit

A better question: What doesn't it get?

Special Movepool: (STAB in Bold)
Land Power
Sludge Bomb
Fire Blast
Flamethrower
Blizzard
Ice Beam
Thunder
Thunderbolt
Surf
Water Pulse
Shadow Ball
Dragon Pulse
Focus Blast
Hidden Power

Again, what doesn't this get?

Support movepool:
Roar
Charm
Disable
Protect
Endure
Stealth Rock
Toxic
Toxic Spikes
Double Team
Flatter
Captivate
Taunt
Torment
Counter

Not as expansive as its other pools, but there's some interesting stuff there.

Alright, so now that we know Nidoqueen has a bajillion moves, the hard part is getting a set from all of it.

Nidoqueen @ Leftovers
Impish (+Def, -SA)
<Rivalry>
EVs: 252 HP/8 Atk/86 SDef
~ Roar
~ Counter
~ Earthquake
~ Avalanche

This is a DP adaptation of the set I use in UU. Switched Ice Beam to Avalanche and Poison Point to Rivalry. This was always a great anti-metagame pokemon that could really mess with physical attackers. Countering back an EQ was always a good way to OHKO something that didn't take into account Nidoqueen's quite decent defensive stats. If it has a Rivalry boost under its belt, Nidoqueen also becomes a formidable attacker. This also works well with Spikes or SR support.

Subpuncher:

Nidoqueen @ Leftovers
<Rivalry>
~ Earthquake
~ Crunch
~ Substitute
~ Focus Punch

Pretty obvious, EVs TBD. 246 Attack Crunch OHKO's Gar with a Rivalry boost (Queen can't OHKO Full HP Gar regardless of EVs), and can OHKO 657HP/130 Def Blissey most of the time. 270(req. +Atk) OHKO's 657/130 Def Blissey all the time.

Special Attacker:

Nidoqueen @ Choice Specs
Rash (+SA, -SD)
<Rivalry>
EVs: 112 HP/8 Atk/136 Speed/252 SA
~ Land Power
~ Ice Beam
~ Shadow Ball
~ Focus Punch

Let me say this, if Blissey catches on to the fact you're a special attacker, thats the time to nuke the female egg with a fat Focus Punch to the face. Also OHKO's Tyranitars that want to get ambitious thanks to the new Sandstorm boost. TBH Nidoking does most of the offensive sets better.

As far as OU goes, Nidoqueen's singular use is as a Heracross counter. With max DF, In Fight is a 3hko. I'd probably consider abusing Counter with max HP and a good helping of defense EVs.

In UU, Nidoqueen has more options. The only real trouble is that Nidoking is better, so you have to make good use of Superpower and maybe Pursuit.

Simply put, Nidoqueen (also Nidoking) is very metagame-centric. It has a lot of moves to use, so the best ones are generally dictated by what opponents you expect to face.

Nidoqueen is a nice variable Pokemon, but seems to be restricted strongly to what you expect to face. It is good but outclassed by many others.

In OU it's better then killing Blissey then Nidoking because of it's attack boost (:

I think the choice specs set is the most valid choice for OU. Attack with special attacks, and finally Focus Punch blissey with a +1 attack boost.

Misty said:

As far as OU goes, Nidoqueen's singular use is as a Heracross counter. With max DF, In Fight is a 3hko. I'd probably consider abusing Counter with max HP and a good helping of defense EVs.

In UU, Nidoqueen has more options. The only real trouble is that Nidoking is better, so you have to make good use of Superpower and maybe Pursuit.

Simply put, Nidoqueen (also Nidoking) is very metagame-centric. It has a lot of moves to use, so the best ones are generally dictated by what opponents you expect to face.

Click to expand...

Interestingly enough, Nidoqueen resists In-Fight, Megahorn, AND Stone Edge (although EQ is BG). Poison/Ground is pretty damn good typing in that respect.