Misdreavus

Type Tier
Ghost OU
Statistics
Stat
HP
60
323
Atk
60
218
Def
60
218
SpA
85
268
SpD
85
268
Spe
85
268
Name Item

Perish Trapper

Leftovers
Moveset
~ Perish Song
~ Mean Look
~ Protect
~ Thunder

Misdreavus is only good for one thing, and that's Perish Trapping. Mean Look whatever, Perish Song, Protect twice, and switch out. Thunder is for Flying phazers (particularly Skarmory) and Suicune.

Other Options

All of these should only go over Thunder: Hypnosis can put stuff to sleep, and Toxic can force a pseudo-hazer to Rest sooner or later. Destiny Bond will make sure that something goes down with Misdreavus, Pain Split can stall a turn, and Confuse Ray could make a pseudo-hazer smack themselves whilst Perish Singing.

Note on Hypnosis: Perish Song + Sleep + Trapping move is banned in many GSC tournaments.

Opinion

Misdreavus is hated by many people. It can't do anything except sit and Mean Look, Perish Song, and Protect. Its stats are rather inferior. Protect's main purpose is to be even more annoying by staying on the screen for more than a turn. Use Houndoom, Tyranitar or something like that to Crunch or Pursuit it away. Or use a Ground-type with Roar while all it can do is precisely nothing. It's one reason why people call GSC nothing but a stallfest, and with Hypnosis it's too good of an anti-staller.

Counters

Pursuit and Roar / Whirlwind are effective ways to combat Misdreavus, especially if on a Ground-type such as Steelix, as they are immune to Thunder. Houndoom is faster and can use Pursuit to slice off two-thirds of its HP on the switch out in fear of Crunch. Tyranitar has the benefit of being able to use both Pursuit and Roar effectively.

You can limit the effectiveness of Misdreavus by using a Pokemon with Curse / Swords Dance and Explosion / Selfdestruct. Raise your Attack as you wait for Perish Song's counter to run down, then use Explosion / Selfdestruct on the final turn. If Misdreavus stays in, you will Explode on a Ghost, but then Misdreavus dies to Perish Song. If it switches, it's going to sacrifice something to Explosion, unless Misdreavus is paired with Gengar or a Rock / Steel Pokemon (and even those will take a huge hit).