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Yes. Only the Pokemon must stay the same. You may use whatever moves/abilities/natures/whatever you want. Make a thread in TRC. Use a similar format to mine. Keep track of your adventure there. You are allowed to Nuzlocke any game you want.
But if i has latias and weavile over alakazam and kyurem, things might have gond a little differently
but im still in the process of improving the team