There's no Vileplume NU analysis posted yet, but I'd like to recommend a physically defensive set that uses Effect Spore to nab status from contact moves and walls many NU threats.
Here's the gist of it:
Vileplume @ Black Sludge
Effect Spore
252 HP / 252 Def / 4 SpD
Bold (+Def, -Atk)
~Sludge Bomb
~Giga Drain
~Moonlight
~Aromatherapy / Sleep Powder
-I'm not sure if Sleep Powder is legal with Effect Spore, but the rest is
-The general idea is to get some defensive use out of Vileplume's new ability. -It takes little damage from Choice Scarf Sawk, survives Samurott's +2 Megahorn and regains HP with Giga Drain (no OHKO though), and can generally come in on non-super effective physical attacks, run the risk of Effect Spore going off (U-turn makes contact, which can be very useful if you're lucky), spread poison with Sludge Bomb, support the team with Aromatherapy and possibly stall things out with Moonlight
-Leech Seed is unfortunately illegal with Effect Spore. Although Protect + Leech Seed would be helpful, Giga Drain and Moonlight do the healing job.
-It also makes a good all-purpose Grass-type switch in, threatening Tangela and Meganium with STAB Sludge Bomb.
-Although generally Vileplume runs a Specially Defensive EV spread, Physically Defensive gives more use to Effect Spore and provides it with a new role, which is especially important since it gets no use out of Chorophyll outside of a sun sweeper set.
Here's the gist of it:
Vileplume @ Black Sludge
Effect Spore
252 HP / 252 Def / 4 SpD
Bold (+Def, -Atk)
~Sludge Bomb
~Giga Drain
~Moonlight
~Aromatherapy / Sleep Powder
-I'm not sure if Sleep Powder is legal with Effect Spore, but the rest is
-The general idea is to get some defensive use out of Vileplume's new ability. -It takes little damage from Choice Scarf Sawk, survives Samurott's +2 Megahorn and regains HP with Giga Drain (no OHKO though), and can generally come in on non-super effective physical attacks, run the risk of Effect Spore going off (U-turn makes contact, which can be very useful if you're lucky), spread poison with Sludge Bomb, support the team with Aromatherapy and possibly stall things out with Moonlight
-Leech Seed is unfortunately illegal with Effect Spore. Although Protect + Leech Seed would be helpful, Giga Drain and Moonlight do the healing job.
-It also makes a good all-purpose Grass-type switch in, threatening Tangela and Meganium with STAB Sludge Bomb.
-Although generally Vileplume runs a Specially Defensive EV spread, Physically Defensive gives more use to Effect Spore and provides it with a new role, which is especially important since it gets no use out of Chorophyll outside of a sun sweeper set.