Dropping a tiny bit of a bombshell here...
Pokémon.
Yep, that's right. Not that I'd want the reboot to replace the ongoing series, but rather exist alongside it. The reason for the need to a reboot is that over time, the Pokédex is becoming a little cluttered, there are hundreds of monsters available, so there is so little you can dedicate to each one to fit them all in. Many of the older Pokémon are also kind of "locked" where they currently are, being cursed by bad movepools, bad typing, bad stats, or just general badness - stemming from the simple fact that they were designed to be early game Pokémon (and the philosophy regarding those can best be summed up with "planned obsolence" - I mean, why should you ever catch more 'mons if the first six you acquire are strong enough to kick ass all throughout your adventure?). Others are just delegated to the job of "dex fodder", never being able to make an impact on anything.
I think Pokémon would benefit a little from a game where there are fewer of the things around. Maybe select 150 or thereabout, change them a little from how they are now (not necessarily design changes, though minor ones could be forgiven - I mean, have you ever seen a photoshopped picture of Garbodor with bigger pupils? It looks a thousand times better, just with that tiny little change). Shake up what is good and what isn't. With fewer models in-game, more time can also be devoted to animating and texturing each individual creature. For once, just outright forget some 500 Pokémon, and give more love to the remaining ones. Same for moves, or for that matter, the battle system entirely. And also, the usual faff about the villainous team. Saving the world gets tacky after a while. Please go back to simple mafia, just for a single game...