I've been using this lead set extensively since the new UU lists and have found it works remarkably at preventing entry hazards and providing momentum for offensive teams with the added bonus of being a last ditch counter to set-up sweepers like CM Raikou.
Status: Complete
[SET]
name: Anti-lead
move 1: Taunt
move 2: Encore
move 3: Counter
move 4: Psychic/Reflect/Light Screen
item: Focus Sash
ability: Inner Focus
nature: Timid
evs: 252 Spe/252 SpA/4 HP
[SET COMMENTS]
<p>Alakazam's blistering Speed and access to Taunt makes it a prime candidate for preventing entry hazards from opposing leads. It outspeeds all of the common UU leads bar Electrode and can thus prevent all forms of entry hazards; although a Jolly Dugtrio can use Stealth Rock if it wins the speed tie, though that situation is exceedingly rare.</p>
<p>EVs are fairly straightforward: maximizing Alakazam's speed and offensive ability, with the remainder in HP. For sets that run Reflect or Light Screen over Psychic, the SpA EVs are not needed and can be replaced with HP EVs. Optionally, dropping the Def IV to 0 can give you a small boost to Counter's power.</p>
<p>While seemingly unorthodox, Counter is the main attack move of the set. Taunt ensures that the opposing Pokemon will use an attack move, thus removing most of the prediction necessary to use Counter. Due to his extreme physical frailty, Counter will almost always net an OHKO on a Pokemon that attempts to kill it with a physical attack. This is especially effective against leads like Honchkrow who use Pursuit, and leads that use a super effective U-turn like Uxie, Mespirit, and Ambipom. Counter combined with Inner Focus also prevents Fake Out leads from breaking Focus Sash, providing clean OHKOs on lead Ambipom, Persian, and Kangaskhan. Counter also defeats many of the primary switch-ins to Alakazam's other sets, like Umbreon, Drapion, and Honchkrow.</p>
<p>Encore provides an answer to stat-up leads and Baton Pass leads, preventing them from being able to utilize any boosts they may accrue; however, the true power of Encore comes in conjunction with Taunt and the Focus Sash. If Alakazam successfully prevents entry hazards with Taunt, Alakazam can come back into play even at 1 HP and Encore many dangerous stat-up sweepers like Nasty Plot Mismagius and Calm Mind Raikou. Encore also serves as an answer to Sucker Punch, allowing you to avoid the damage and get a free switch out of the deal.</p>
<p>The last move is open for interpretation. The preferred move is Psychic, as it gives you reliable offensive power as well as a way to hit special-based leads like Froslass (who is 2HKO'd even with max HP EVs) and Moltres. It also allows Alakazam to perform minimal revenge kills later in the game as Psychic hits common threats like Venusaur and Hitmontop for super effective damage. Other options include Reflect and Light Screen for team support. The fact he can only carry one at a time and cannot have Light Clay with this set means they are a somewhat inferior option, but Taunt and Focus Sash virtually guarantees that he will get his one screen up, allowing you to set up a sweeper or entry hazards easily.</p>
<p>This set's worst nightmare is Spiritomb because it is immune to both Counter and Psychic and can hit Alakazam hard with a STAB Pursuit, Shadow Ball, or Shadow Sneak. The only way to effectively eliminate this set is for a lead to U-Turn to Spiritomb with Pursuit. This set also doesn't like being tricked a Choice Scarf by Uxie or Mespirit, although most tend to set up Stealth Rock or U-Turn instead.</p>
<p>With Alakazam preventing entry hazards, Stealth Rock weak sweepers like Life Orb Moltres and Nasty Plot Houndoom can easily come in without having to worry about losing 50% and 25% of their HP respectively. Houndoom is especially great because it can set up on all forms of Spiritomb with impunity. Light Screen versions work very well with Rock Polish Rhyperior and Aggron, who can set up on Spiritomb (but be careful of Will o Wisp if you do not have Lum Berry) and other physical attackers that commonly take out Alakazam, while Light Screen prevents Milotic and other physical tanks (who commonly use special attacks) from killing them outright. Reflect versions are perfect with Sub/CM Raikou as it prevents Spiritomb from being able to break his Sub with anything, and allows him to survive an unSTAB Earthquake from most anything in the tier.</p>
Status: Complete

[SET]
name: Anti-lead
move 1: Taunt
move 2: Encore
move 3: Counter
move 4: Psychic/Reflect/Light Screen
item: Focus Sash
ability: Inner Focus
nature: Timid
evs: 252 Spe/252 SpA/4 HP
[SET COMMENTS]
<p>Alakazam's blistering Speed and access to Taunt makes it a prime candidate for preventing entry hazards from opposing leads. It outspeeds all of the common UU leads bar Electrode and can thus prevent all forms of entry hazards; although a Jolly Dugtrio can use Stealth Rock if it wins the speed tie, though that situation is exceedingly rare.</p>
<p>EVs are fairly straightforward: maximizing Alakazam's speed and offensive ability, with the remainder in HP. For sets that run Reflect or Light Screen over Psychic, the SpA EVs are not needed and can be replaced with HP EVs. Optionally, dropping the Def IV to 0 can give you a small boost to Counter's power.</p>
<p>While seemingly unorthodox, Counter is the main attack move of the set. Taunt ensures that the opposing Pokemon will use an attack move, thus removing most of the prediction necessary to use Counter. Due to his extreme physical frailty, Counter will almost always net an OHKO on a Pokemon that attempts to kill it with a physical attack. This is especially effective against leads like Honchkrow who use Pursuit, and leads that use a super effective U-turn like Uxie, Mespirit, and Ambipom. Counter combined with Inner Focus also prevents Fake Out leads from breaking Focus Sash, providing clean OHKOs on lead Ambipom, Persian, and Kangaskhan. Counter also defeats many of the primary switch-ins to Alakazam's other sets, like Umbreon, Drapion, and Honchkrow.</p>
<p>Encore provides an answer to stat-up leads and Baton Pass leads, preventing them from being able to utilize any boosts they may accrue; however, the true power of Encore comes in conjunction with Taunt and the Focus Sash. If Alakazam successfully prevents entry hazards with Taunt, Alakazam can come back into play even at 1 HP and Encore many dangerous stat-up sweepers like Nasty Plot Mismagius and Calm Mind Raikou. Encore also serves as an answer to Sucker Punch, allowing you to avoid the damage and get a free switch out of the deal.</p>
<p>The last move is open for interpretation. The preferred move is Psychic, as it gives you reliable offensive power as well as a way to hit special-based leads like Froslass (who is 2HKO'd even with max HP EVs) and Moltres. It also allows Alakazam to perform minimal revenge kills later in the game as Psychic hits common threats like Venusaur and Hitmontop for super effective damage. Other options include Reflect and Light Screen for team support. The fact he can only carry one at a time and cannot have Light Clay with this set means they are a somewhat inferior option, but Taunt and Focus Sash virtually guarantees that he will get his one screen up, allowing you to set up a sweeper or entry hazards easily.</p>
<p>This set's worst nightmare is Spiritomb because it is immune to both Counter and Psychic and can hit Alakazam hard with a STAB Pursuit, Shadow Ball, or Shadow Sneak. The only way to effectively eliminate this set is for a lead to U-Turn to Spiritomb with Pursuit. This set also doesn't like being tricked a Choice Scarf by Uxie or Mespirit, although most tend to set up Stealth Rock or U-Turn instead.</p>
<p>With Alakazam preventing entry hazards, Stealth Rock weak sweepers like Life Orb Moltres and Nasty Plot Houndoom can easily come in without having to worry about losing 50% and 25% of their HP respectively. Houndoom is especially great because it can set up on all forms of Spiritomb with impunity. Light Screen versions work very well with Rock Polish Rhyperior and Aggron, who can set up on Spiritomb (but be careful of Will o Wisp if you do not have Lum Berry) and other physical attackers that commonly take out Alakazam, while Light Screen prevents Milotic and other physical tanks (who commonly use special attacks) from killing them outright. Reflect versions are perfect with Sub/CM Raikou as it prevents Spiritomb from being able to break his Sub with anything, and allows him to survive an unSTAB Earthquake from most anything in the tier.</p>