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I think the ONLY reason to use M-beedrill is that Adaptability u-turn. Hit and run everything ,and when you can hit with a super effective drill run, knock off, or poison jab when it will do something. If you are using it for knock off there are much better users.
I've lurked on Smogon since B/W, and I finally decided to signup for the forums to post this hypothetical set for Mega-Beedrill.
U-turn
Venoshock
Drill Run
Protect/Toxic Spikes/Knock Off
The idea is that with Adaptability, Venoshock is boosted to a very solid 110 attack even if the opponent...