Type:
Base Form Stats: 95 HP / 75 Atk / 110 Def / 100 SpA / 80 SpDef / 30 Spe
Mega Evo' Stats: 95 HP / 75 Atk / 180 Def / 130 SpA / 80 SpDef / 30 Spe
Abilities: Oblivious / Own Tempo / Regenerator -> Shell Armour
Notable Attacks:
Hydro Pump
Surf
Scald
Whirlpool
Future Sight
Psychic
Psychic Noise
Psyshock
Expanding Force
Stored Power
Body Press
Focus Blast
Blizzard
Ice Beam
Fire Blast
Flamethrower
Grass Knot
Foul Play
Shadow Ball
Weather Ball
Notable Status Moves:
Block
Disable
Skill Swap
Slack Off
Thunder Wave
Trick
Trick Room
Setup Moves:
Amnesia
Belly Drum
Calm Mind
Psych Up
Curse
Iron Defense
Nasty Plot
Pros:
+ Impressive physical bulk (significantly outpacing that of Dondozo and Pecharunt for reference) and good special bulk.
+ Access to strong and useful STAB attacks such as Scald, Future Sight, Psychic Noise, Psyshock and Stored Power.
+ Access to colourful coverage options to hit just about anything it wants .
+ Access to many utility and setup moves allowing for alot of set variety and ways it could be utilized.
+ The addition of Item Clause and very limited items makes the competition between Slowbro with an item and Slowbro with a mega stone close to non-existent, especially on balance and stall teams which will want to have
on something else.+ Due to how good the base form is, it is very unreliant on the mega and so you can very realistically not mega it in alot of games, possibly enabling double mega teams.
+ Its ability Shell Armour solves the main issue with Iron Defense Body Press setup by making it immune to critical hits.
Cons:
- Loss of Regenerator can not be understated as it heavily cripples its ability to not be overwhelmed by the threats it is attempting to wall, and gives even less of a leeway to play around Toxic.
- Despite access to Psychic Noise, it can struggle to use it effectively outside of Trickroom due to its speed being slower than many of our walls such as
- Significant vulnerability to being crippled by Toxic or Will-O-Wisp if attempting an Iron Defense Body Press wincon.
- Weakness to multiple strong offensive threats such as
which can brute force their way through his physical bulk especially if they carry a
to stave off the Scald burns or Thunder Wave paralysis it may attempt using to cripple them.Sets that have been used in other Metagames and have no appearant reason to not work here:
Standard Calm Mind
Slowbro @ Slowbronite
Ability: Regenerator
EVs: 252 HP / 76 Def / 180 SpD
Bold Nature
- Scald
- Calm Mind
- Slack Off
- Ice Beam / Psyshock
Ice beam is useful against
and snipes 
Psyshock aids in CM wars and allows it to beat some SpDef walls.
Trapper CM
Slowbro @ Slowbronite
Ability: Regenerator
EVs: 252 HP / 252 Def / 4 SpD
Bold Nature
- Block / Whirlpool
- Rest / Slack Off
- Scald
- Calm Mind
Slowbro can trap pokemon that can not break it with block and use them as setup fodder, Scald as a mono attacking move is fine due to the meta not having any Water Absorb Pokemon and few 4x resists.
Slack Off is more reliable however Rest allows Slowbro to not be beaten by status such as toxic from the pokemon it trapped.
Offensive 3A Slack Off
Slowbro @ Slowbronite
Ability: Regenerator
EVs: 212 HP / 252 SpA / 44 Spe
Modest Nature
- Scald
- Slack Off
- Ice Beam
- Psyshock / Fire Blast / Flamethrower / Future Sight
Fire Blast allows it to OHKO Bulky
after Mega Evolving however Flamethrower can be used as a more reliable option that requires some chip such as Stealth Rock.Future Sight can be used to support Pokemon such as
44 Speed allows it to outspeed 4 Speed IVs
to hit it with Psyshock.Sets utilizing its new tools:
Iron Defense Body Press Slack Off
Slowbro-Mega @ Slowbronite
Ability: Shell Armor
EVs: 252 HP / 212 SpD / 44 Spe
Calm Nature
- Body Press
- Slack Off
- Psychic Noise
- Iron Defense
44 Spe is used to outspeed
with 4 speed IVs.SlowDemon
Slowbro-Mega @ Slowbronite
Ability: Shell Armor
EVs: 252 HP / 212 SpD / 44 Spe
Calm Nature
- Body Press
- Stored Power
- Calm Mind
- Iron Defense
This set utilizies Shell Armor and both methods of increasing bulk that Slowbro has to sweep teams
Physical Fighting + Special Psychic is one of the best coverages out there and you can very well get in a setup war with almost any Psychic type in the tier and win.
is the set's biggest issue so make sure to get rid of it before attempting a sweep.Bulky Support
Slowbro @ Slowbronite
Ability: Regenerator
EVs: 252 HP / 252 Def / 4 SpD
EVs: 252 HP / 76 Def / 180 SpD
Bold Nature
- Scald
- Future Sight
- Slack Off
- Thunder Wave / Foul Play / Body Press
Body Press could be used as a way to lure
both spreads OHKO it, however the earlier is more reliable against 5 Fallen / Black GlassesOther Intresting Options:
Skill Swap could be used on Setup sets to take away Unaware from
and take Purifying Salt from 
to fix your vulnerability to status.Psych Up could be used instead of CM/ID/Amnesia to instantly match a CM/IDBP/BU/QD sweeper's defensive boosts to wall them way more effectively after surviving one hit, a task that should not be too hard with such monstrous bulk.
Good Teammates:
(Magic Guard) Can absorb status for it and beat
Switches into toxic and beats many of Slowbro's checks notably 
Benefit from Future Sight support and Slowbro crippling opposing pokemon with Thunder Wave.
Benefit from Future sight support and threaten with the later having access to Defog, which Slowbro appreciates after Mega Evolving.
Hazards make it significantly more difficult for opposing breakers to switch around Slowbro, and after Mega Evolving, Slowbro becomes vulnerable to hazards, both of these Pokemon provide hazards and removal, Toxic Spikes being specially good due to Slowbro threatening common poison types.Notable Checks:
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