Vs AD lane bullies, I go 3 armor quints, 9 flat armor seals, 9 ad marks, 9 cdr glyphs as Nasus with 9-21-0. That way I can survive lane, get strong, and carry. People run armor penetration marks but its too easy to get zoned so I like to last hit more easily and lifesteal more easily. If I am vs a lane which isn't as hard, I take 3 MS quints, 9 flat armor seals, 9 armor pen marks, and 9 CDR glyphs.