I started using hacked Rare Candies and Vitamins in the later parts of my nuzlockes some time ago. It simply saves tons of time when a member dies, as most games were not designed for randomly taking a LV4 Mon from Route 1 and getting him up to like LV30.
Time is on short supply so it is just convenient, but I can understand people not wanting too do that
It can make stuff too easy if you use it to swap to the perfect team each major battle, but I try to avoid that.
As for Set-Up it is usually a context issue. I mostly avoid trying to Set-Up Sweep but sometimes Cheese is your only option (for example, Gen 3 Walter is just stupid without Marshtomp or Geodude, and I don't pick Mudkip because it's so good)
The good thing about nuzlockes is how customizable the ruleset is, simply play how you like
Time is on short supply so it is just convenient, but I can understand people not wanting too do that
It can make stuff too easy if you use it to swap to the perfect team each major battle, but I try to avoid that.
As for Set-Up it is usually a context issue. I mostly avoid trying to Set-Up Sweep but sometimes Cheese is your only option (for example, Gen 3 Walter is just stupid without Marshtomp or Geodude, and I don't pick Mudkip because it's so good)
The good thing about nuzlockes is how customizable the ruleset is, simply play how you like