Would it really make anybody happier if the title was "Would a Substitute Blissey work?"
Why don't you just attack on the switch? You are going to be taking a hit based on the damage calcs you made so you might as well damage the switch-in and give yourself a better chance of surviving an attack without the 25% health drop. That also allows you to use Softboiled so this thing can actually come back in again....Except most Special attackers.
Substitute is mainly there to block the incoming Physical attack while Blissey takes whatever they brought in to take it down. Softboiled could be added in there... If you're willing to lose the chance of a supereffective hit on something.
It doesn't lose diversity by giving it Softboiled lol. What is Substitute doing on that set?
The question is if you can predict exactly what they'll be switching in. Which is kind of difficult considering the number of Pokemon that Blissey generally has problems with. Focus Blast isn't exactly a great idea if they send in an Infernape.
XD He IS the OP.Thats why you use substitute on the switch so you can see what they switch in. Did you even read the OP? or did you just look at the set and calcs.
XD He IS the OP.
I was saying did you read the ORIGINAL POST. That just happens to have the same abreviation.
also, to make this relevant
subbing on the switch to an infernape does nothing. If you do max 83% to infernape with psychic as it is, then he breaks your sub and kills you, doing a lot worse than if you had just attacked on the switch.
Note: May actually be fun with serene grace, with higher chances of SDEF drop, para, or freeze.
Apparently most Infernapes use Close Combat to break the Sub. Raising it to an OHKO with Infernape's Defense drop. Go figure.
It would be pretty fun.
Rest of post still applies. Blissey should never be your answer to infernape.