I was theorymoning a SubSplit Medicham in gen IV:
Adamant/Jolly Medicham@LO
~Substitute
~Pain Split
~High Jump Kick
~Psycho Cut/Rock Slide
i don't think that this set would work at all for gen 5. medicham is way too frail to effectively pull this off, and its speed is really only average at best, especially when compared to all of the speedy new threats that can be found this generation. if you're going to use medicham at all, a scarf set is the way to go, though a choice band could be quite damaging. while the above set does find some opportunities to setup on nattorei (who is so ridiculously common that it makes me want to puke), many other pokemon can just outspeed and shit all over it, so i don't really think that it's worth it. when an uu tier is formed, though, this set may be worth testing.