Here's a little set I've been using in RU, and now UU for some time, and I can say it has been amazing and quite effective.
QC: [PK Gaming] [Moo] [Snunch]
GP: [Shame That] [sandshrewz]
[SET]
name: Substitute + Calm Mind
move 1: Calm Mind
move 2: Substitute
move 3: Psychic / Psyshock
move 4: Thunderbolt
item: Leftovers
nature: Timid
evs: 96 HP / 188 SpA / 224 Spe
[SET COMMENTS]
<p>Uxie is quite fast for a defensive Pokemon; by utilizing both Substitute and Calm Mind, along with its great defensive stats, it can surprise and overcome some of its usually more troublesome opponents. Although one might immediately compare Uxie to Mew, who has overall better bulk, slightly better Speed, as well as better offenses, it lacks the Ground-type immunity Uxie sports, making Mew vulnerable to Spikes and Toxic Spikes. Calm Mind boosts Uxie's already great Special Defense, and raises its Special Attack to threatening levels. Substitute blocks dangerous status such as paralysis and Toxic poison, and after a few Calm Mind boosts, Uxie's Substitutes are sturdy enough to withstand most special attacks, even some super effective ones. Psychic is Uxie's most powerful attack, and can destroy anything that does not resist it after a few boosts. Thanks to Uxie's immense bulk, it isn't too difficult to accumulate many boosts. Thunderbolt complements Psychic nicely, landing neutral hits on most things that either resist or are immune to Psychic, with the exception of Krookodile and Steelix—both of which are relatively uncommon in the UU metagame. Psyshock is a viable alternative over Psychic in order to do more damage to special walls, but its lower Base Power makes it less appealing.</p>
[ADDITIONAL COMMENTS]
<p>The given EV spread along with a Timid nature allows Uxie to outspeed Rotom, which is arguably the most important thing Uxie needs to outrun, and provides a little more bulk with the 96 HP EVs; the remaining EVs are put into Special Attack in order to ensure that Uxie isn't completely useless without any boosts. An alternate EV spread that maximizes HP and Defense along with a Bold nature can be used in order to take hits better while setting up, but the loss of power and Speed is extremely noticeable. Leftovers should be the only option for this set, as Uxie has no other form of recovery, and appreciates any replenished health, no matter how little. Giga Drain is an option over Thunderbolt in order to hit Krookodile and provide a form of pseudo-healing, but its low Base Power and inferior coverage usually isn't worth it.</p>
<p>As this set aims to attempt a sweep rather than to support the rest of the team, Uxie actually needs assistance from the team in order to be successful. Teammates that are able to set up entry hazards, the most useful being Toxic Spikes as it can wear down the opponent while Uxie sets up, are extremely useful. Qwilfish is an excellent teammate, as it can set up both Toxic Spikes and Spikes, as well as having the ability Intimidate, and access to useful support moves such as Taunt, Thunder Wave, and Haze. Teammates that can get rid of Krookodile and other Dark-types in general are needed, as the latter are immune to Psychic. Bulky Fighting-types such as Hitmontop, Machamp, Cobalion, and Hariyama fit the bill nicely.</p>
QC: [PK Gaming] [Moo] [Snunch]
GP: [Shame That] [sandshrewz]
[SET]
name: Substitute + Calm Mind
move 1: Calm Mind
move 2: Substitute
move 3: Psychic / Psyshock
move 4: Thunderbolt
item: Leftovers
nature: Timid
evs: 96 HP / 188 SpA / 224 Spe
[SET COMMENTS]
<p>Uxie is quite fast for a defensive Pokemon; by utilizing both Substitute and Calm Mind, along with its great defensive stats, it can surprise and overcome some of its usually more troublesome opponents. Although one might immediately compare Uxie to Mew, who has overall better bulk, slightly better Speed, as well as better offenses, it lacks the Ground-type immunity Uxie sports, making Mew vulnerable to Spikes and Toxic Spikes. Calm Mind boosts Uxie's already great Special Defense, and raises its Special Attack to threatening levels. Substitute blocks dangerous status such as paralysis and Toxic poison, and after a few Calm Mind boosts, Uxie's Substitutes are sturdy enough to withstand most special attacks, even some super effective ones. Psychic is Uxie's most powerful attack, and can destroy anything that does not resist it after a few boosts. Thanks to Uxie's immense bulk, it isn't too difficult to accumulate many boosts. Thunderbolt complements Psychic nicely, landing neutral hits on most things that either resist or are immune to Psychic, with the exception of Krookodile and Steelix—both of which are relatively uncommon in the UU metagame. Psyshock is a viable alternative over Psychic in order to do more damage to special walls, but its lower Base Power makes it less appealing.</p>
[ADDITIONAL COMMENTS]
<p>The given EV spread along with a Timid nature allows Uxie to outspeed Rotom, which is arguably the most important thing Uxie needs to outrun, and provides a little more bulk with the 96 HP EVs; the remaining EVs are put into Special Attack in order to ensure that Uxie isn't completely useless without any boosts. An alternate EV spread that maximizes HP and Defense along with a Bold nature can be used in order to take hits better while setting up, but the loss of power and Speed is extremely noticeable. Leftovers should be the only option for this set, as Uxie has no other form of recovery, and appreciates any replenished health, no matter how little. Giga Drain is an option over Thunderbolt in order to hit Krookodile and provide a form of pseudo-healing, but its low Base Power and inferior coverage usually isn't worth it.</p>
<p>As this set aims to attempt a sweep rather than to support the rest of the team, Uxie actually needs assistance from the team in order to be successful. Teammates that are able to set up entry hazards, the most useful being Toxic Spikes as it can wear down the opponent while Uxie sets up, are extremely useful. Qwilfish is an excellent teammate, as it can set up both Toxic Spikes and Spikes, as well as having the ability Intimidate, and access to useful support moves such as Taunt, Thunder Wave, and Haze. Teammates that can get rid of Krookodile and other Dark-types in general are needed, as the latter are immune to Psychic. Bulky Fighting-types such as Hitmontop, Machamp, Cobalion, and Hariyama fit the bill nicely.</p>
