Nope, haven't played Pt since... like, a while ago. I've never RNGd in Pt., so sadly I won't be able to help much with Pt. abuse :( I can always help you with hitting your seed, though, since I'm sure it's fairly similar to hitting a seed in HGSS (I think).
But, I don't think NPCs make a difference. Even if the NPCs advance the frame, they won't change the delay you hit ;)