Lum Berry and Safety Goggles can both screw Breloom over a lot, especially if you make a habit of going for the first turn Spore. Leads with priority can take Breloom out in two turns while only having to risk one turn of action on Breloom's side, making Lum Berry + priority a great combination for taking Breloom down quickly. Sometimes Azumarill carry Lum Berry, for example, so if your opponent leads with an Azumarill vs your Breloom don't waste time and go straight for the Bullet Seed. Mega Heracross is another Pokémon that beats Breloom up a bunch. If it speed creeps for base 70s, it can outspeed on the first turn and bust straight through you with Skill Link Pin Missile. Obviously this also applies for other Skill Link/multihit abusers like Mamoswine or the very rare Cincinno - Cloyster isn't as much of a problem as it is naturally slower and can just be Spored. Most other things are ether really rare or sort of random, like Sleep Talk on choiced mons like Talonflame or the occasional Insomnia/Vital Spirit carrier, although those are rare enough to be negligible.
