I think Rotom-W is pretty good in general, but I personally would stick to the suggested "standard" and "choice" sets.
Sure, trick can steal an important item, but unless you give them an item back that is going to cripple them, that slot is much better off with a different move. Imo a move like volt switch is better because it can help you gain momentum even if you aren't running a choice set.
I've been trying out a Scolipede lead set.
I think Scolipede can effectively counter most leads or at least allow you to get the one up on the opponent in some way every time. Sorry for the lengthy post, but for all I know, it needs the heavy explanation.
"Leadipede"
Scolipede @ Focus Sash, Poison Point (he will be even better when DW quick feet is released)
Adamant - 252 attack/ 252 speed / 4 doesn't really matter (I suppose hp)
Megahorn, Agility, Baton Pass, Spikes
The first one up is: no one uses the bug right now (Bug Poison type btw if you don't know him either) They haven't seen this set before and generally assume all out SD attacker with some of EQ, rock slide, megahorn, poison jab, pursuit.
For hazard leads:
If you notice the opponent's team has a minimal resistance to bug, agility and do pretty heavy damage with Megahorn.
If there is decent bug resist on their team, agility then bp to a slow but powerful early sweeper.
If you see they have a weakness to hazards and decide to set your own hazards, start spiking up.
(remember focus sash can save you if, for example, a Forretress decides to explode on you as you agility)
For prankster leads:
Almost all prankster leads are weak to bug bar the genies(I admit the common genies give this set the most problem). Just Megahorn them for heavy damage. Scolipede is pretty fast even at adamant (112 base speed) so you can usually get the jump status leads (generally won't even matter except for sleep after quick feet is out). And for other suspected non-prankster taunts, if Megahorn is not resisted go for it. However, it might also be a good choice to switch Scolipede out and try to set up later especially if they resist bug.
For attacking leads:
If they are bug weak, go for the megahorn.
If they have priority, either switch or attack.
If they are most other attacking leads that don't follow the above situations, either spike or set up your early sweeper with a bp agility.
While focus sash is obviously for the ability to at least do something 99.9%, his bulk is surprising.
Somehow I managed to kill an opponent's Garchomp with Megahorn's 2HKO after surviving an Outrage with 7% left. (resulting in my sig) ...I know, low damage roll on a def. Chomp or something.
Anyway, he has rarely let me down, generally surprised opponents, and is fun no matter what!
I'm not going to pretend that I'm good at gen 5 OU, so if you see faults after trying him out, let me know. Also if you know of a lead that can do what he does better, let me know! My team will be happy to have them. (yes, argue that there is no true lead, but if they can't tell that Scolipede is lead material, you always have surprise factor)