Yeah, while I would love to see it, if locations in the Pokemon World are ever going to be on the table it'll probably be down the line IF the collab is successful and they decide to keep going with it.
But I feel the first sets will be focused on simpler concepts:
1. Pokemon Sets. The most obvious, we'll get sets where it's just the Pokemon made from Lego. They'll be the most popular Pokemon of course, and I'd assume one set will contain enough pieces to build each stage of the entire evolution line (obviously not all at the same time, you'll need to buy multiple sets to do that);
Think of the 3-in-1 Creator Sets. Of course, while that works for some families like the Starters, there will also be some special cases. I can see some bigger sets where they do provide enough pieces to have all stages of the evolution line (the models likely will be smaller than the 3-in-1 sets); I can imagine Pikachu being one (along with Pichu, Raichu, & Alolan Raichu), and possibly even one super big (and expensive) one for Eevee and its evolutions.
2.
BrickHeadz. Essentially Lego Funko Pops that you build. While we're certainly get a few Pokemon ones, likely the usual suspects, this could also be where we may see the human characters. Thinking Cynthia, N, Lillie, Zinnia, Leon, Nemona, etc.. They could even have an Ash and
have a 8in1 for him like they did for Batman.
3. Objects. Lego has also delved into
making iconic objects such as helmets (especially from Star Wars & Marvel Comics; though they also have done things like the Infinity Gauntlet and Shadow the Hedgehog's head). And what better objects to do this with than the Poke Balls? Or how about some of the Pokedexes? Lego also has
a line of batonical sets, maybe have similar sets but you make various Berries. Or maybe a batch of Evolution Stones. If they want to reach I think the designs of Potions and other sprays are iconic enough, though those may be a "later if successful" idea. Oh, if they don't want a BrickHeadz of Ash, they could instead just gave sets based on his hats WHICH are game canonical via the Ash Hat Pikachus.
4. Art & Maps. Ever willing to experiment, Lego has done
"flat" sets based on famous pieces of art and maps, though obviously able to have layers to them. I'm thinking this would be a fun way to have the Badges as a set. They could also have a Lego version of region maps, depending on how much detail they want to go into. If they want to go meta they could have art sets based on the game art covers, maybe even have it be a sort of working box with a cartridge made of Lego inside.
5.
Architecture. While I think a full playset is not in the cards atm, maybe some sets based on well known buildings or structures isn't out of the question. OR, maybe even a small, condensed diorama of a town/city.
Bonus.
Minifigures. Hm, I'd say that's up in the air. Like, would make sense, start a Pokemon blind bag series and have at least 9 gens worth of minifigs. Heck, they're doing some interesting stuff with
Disney sets which I think they could transfer to Pokemon; A set based around a character that comes with a minifig of them, some of their iconic Pokemon, and maybe some other objects or set pieces related to that character.
Depending on how far they can push it, there's a lot that can be done. I don't think we'll get anything like the Mario-like playsets; like I can think of some ways they can do it (thinking back to stuff like Hasbro's
THINKChip and
V-Trainer figures), but honestly may just be best to let any interactive battles left to the games.