Protect and endure together is probably a waste, since the use of one reduces the chance of success of the other. You can't have a guaranteed protect followed by a guaranteed endure, if that's what you're thinking.
Thus, go for Sub + SD. You should be able to pass several speed boosts, and you might be able to pass a Sub and/or attack boosts too.
EDIT: Smogon's sets suggest Leftovers when using Substitute, that way you can sub 5 times. But a pinch berry might be a good alternative. You could even use the one that boosts special attack (Petaya Berry), then pass to a special or mixed sweeper instead of a physical.
Another item option is Mail, since it can't be tricked, thus thwarting attempts to give you a Choice Scarf.
Thus, go for Sub + SD. You should be able to pass several speed boosts, and you might be able to pass a Sub and/or attack boosts too.
EDIT: Smogon's sets suggest Leftovers when using Substitute, that way you can sub 5 times. But a pinch berry might be a good alternative. You could even use the one that boosts special attack (Petaya Berry), then pass to a special or mixed sweeper instead of a physical.
Another item option is Mail, since it can't be tricked, thus thwarting attempts to give you a Choice Scarf.