Okay I have two sets, both are anti-leads.
Anti-Lead V2.0
Nature: Jolly/Timid
EV's: 4 HP/252 Def/252 Spe
Ability: Own Tempo
Held Item: Focus Sash
Protect/Encore
Magic Coat
Stealth Rock
Taunt/Spore
The way this set is played is differently from the other anti-lead set. Depending on what you're facing, you use a different move. Against sleep-inducing leads like Roserade and other Smeargle, begin with Magic Coat and bounce their sleep move right back at them, giving you the advantage. Proceed by setting up rocks while they switch out, then Protect (to scout the opponents next move), or switch out to an appropriate counter. Against slower leads like Swampert or Hippowdon, Taunt or Spore is the move to use. Spore is more effective in the wau that it completely disables them until they wake up, while Taunt can stop them if they decide to switch to something like Tauntados, SleepTalkDos, Curselax, or other things that can absorb status and set up. Against faster leads that have Taunt, such as Azelf, or Aerodactyl, you have two options. The first is to Protect and scout what they will do (Most likely Taunt or Attack), then depending on what they do, you should probably switch out to something else. Faster Taunters are the bane of this set.
For the first and last slot, there are pros and cons to each. Protect makes an excellent scouting move, while Encore can disable slower leads. Protect tends to be the more effective move because it can avoid the ominous Fake Out. Between Taunt and Spore, Spore seems to usually be the better choice because you have the ability to completely disable opposing slower leads.
Anti-Lead V1.0
Nature: Jolly
EV's: 90 HP/168 Def/252 Spe
Ability: Klutz
Held Item: Choice Scarf
Fake Out
Magic Coat/Protect
Baton Pass
Switcheroo
Lopunny's unique ability Klutz is both a blessing and a burden. On the upside, you aren't negatively affected when you are tricked into a shitty item you don't want. On the downside, items with positive effects don't work on you either. So to remedy this, Lopunny given the Choice Scarf with the move Switcheroo can cause havoc on the enemy.
Depending on the lead you are facing, you have a multitude of options to choose from. Against much slower leads (like Hippowdon, Swampert, or Forretress), use Switcheroo followed by Baton Pass. Baton Passing without any boosts may seem like a horrible idea at first, but remember that if the opponent switches (they most likely will seeing as they have a Choice Scarf attatched now), you move second. They switch, you use Baton Pass, and you can safely switch to a reliable counter without worry. Against Infernape leads (or other slower leads with Fake Out), use Fake Out (assuming the opponent is using the set on the smogon strategy dex then you will be faster) to break the sash, then Switcheroo (they will most likely use Close Combat so another choice is to Baton Pass to a ghost/fighting resistant type who can KO them). Against faster taunting leads like Azelf and Aerodactyl, your only real choice is to Fake Out, then switch to an appropriate counter. Against slower Taunters use Fake Out followed by Switcheroo. Against sleep-inducing leads like Roserade, Fake Out to break the sash, then Magic Coat to reflect their sleeping move right back in their faces. There are a multitude of other options against opposing leads, but I won't list all of them because that would take a long time.