nobody runs 4/0 blissey, where would the other 256 EVs be >_> besides a +1 focus blast has a pretty good chance of 2hkoing some blissey variants if you're LO. if you aren't LO, the worst blissey can do to you is status (lum that shit) or seismic toss as you boost again and hit it.
you CAN run close combat as a lure, but there is a different set that is better suited to that, which was the mixed viriz with work up. it's not really about work up on that set, the boost is really just there as an option if you ever get an opening. on your current set, chances are you're better off with focus blast for more power against most opponents.